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Data availability X-ray crystallographic data are available from the PDB under accession numbers 6U32 (reference), 7ZBA, 7ZBB and 7ZBD
Part of it was used for this article (US Government public domain), specially for drug and other interactions
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URL Trujillo JM, Nuffer W, Smith BA
Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting
Studies in rats [61] also suggested that both VPA and its unsaturated metabolites inhibit -oxidation through different mechanisms, such as sequestration of CoA-SH and direct inhibition of specific enzymes in the -oxidation sequence by CoA esters, particularly 4-en-VPA-CoA
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