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Likewise, a 2010 phase III, randomized, double-blind, placebo-controlled, parallel-group study undertaken in Europe found that MT1 reduced the severity of PLE when administered as a 16 mg implant over a four-month period [14]

[2], who observed that the liver of the OLZ-treated group had increased portal area congestion, severe lipid alterations, inflammatory infiltration, and vacuolization of hepatocytes

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