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In tissue-repair research, cell migration matters because the cells that perform repair (fibroblasts, endothelial cells, immune cells) need to physically arrive at the site to do their work

The most common issues reported include gastrointestinal effects such as nausea, diarrhea, and vomiting

PRP has the advantage of a deeper evidence base with more randomized controlled trials and broader acceptance in mainstream medicine

Reasons for the difference by type 2 diabetes status may be related to more general reasons why it is often more difficult for individuals with type 2 diabetes to lose weight

Keen JH et al

Immunomodulatory therapeutic effects of curcumin on M1/M2 macrophage polarization in inflammatory diseases