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Hypoxia-inducible factors 1 and 2 (HIF-1 and HIF-2) exert different effects on lipid metabolism [50]
Several studies have reported that supplementing rats with both L-carnitine and alpha-lipoic acid halts age-related increases in reactive oxygen species (ROS), lipid peroxidation, protein carbonylation, and DNA strand breaks in heart, skeletal muscle and brain, concomitant with improvement in mitochondrial enzyme and respiratory chain activities [146149]
In: FASEB journal: official publication of the Federation of American Societies for Experimental Biology
10.55563/clinexprheumatol/9sdln5 138 QianX.JiangY.LuoY.JiangY
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