At higher serum levels, the effective half-life increases, promoting drug accumulation
This makes it a valuable tool for individuals suffering from conditions such as Crohns disease, ulcerative colitis, and irritable bowel syndrome (IBS) (Sikiric et al., 2016)
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Intracellular lipid peroxide (LPO) detection To detect the intracellular LPO content, 143B cells were incubated with PBS, Ru(II)-OH, NP2, and NP4 (Ru 10 M) for 6 h
LCMS data analysis The diaPASEF raw file processing, control of peptide-level and protein-level false discovery rates (FDRs), assembly of proteins from peptides and protein quantification from peptides were performed using library-free analysis in DIA-NN (version 1.8) 72