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Furthermore, combination therapy was associated with a mean 3.22 kg reduction in body weight and did not increase the risk of hypoglycaemia (RR 0.99) versus other therapies

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Birsoy and colleagues also found how mitochondrial glutathione drives cancer spread: not by acting as an antioxidantan effect ruled out through multiple experimentsbut by signaling to activate ATF4, a transcription factor that helps cancer cells survive in low-oxygen conditions