Exclusion criteria were as follows: type 1 diabetes or positivity for anti-glutamic acid decarboxylase autoantibodies, secondary forms of diabetes, acute metabolic complications, liver disease, renal dysfunction or patients under anticoagulant treatment, previous bariatric surgery, congenital or acquired abnormalities of the digestive tract, pregnancy, nursing or desired pregnancy in the 12 months following inclusion, and corticoid use by oral or intravenous route for more than 14 consecutive days in the last 3 months
Then doctors started noticing the side-effect of weight lossand now here we are
otherwise even a large list-price gap will not force rapid switching in premium markets, while emerging markets tilt quickly to the lowest credible supplier
Value Beyond Cost Consider the return on investment including improved health and wellness, enhanced performance and recovery, better quality of life, potentially reduced other healthcare costs, and prevention of age-related decline
Beyond amyloid, emerging targets include tau, neuroinflammation and neurotransmitters
Sykes DL, Holdsworth L, Jawad N, Gunasekera P, Morice AH, Crooks MG