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Users of any of these compounds should discuss their use with a physician who can monitor for adverse effects and advise on contraindications including for BPC-157, which carries an unresolved angiogenesis risk that is particularly relevant for individuals with active or suspected cancer

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The figure describes an in-vitro dendritic-spine assay in which picomolar Dihexa produced spine density comparable to nanomolar BDNF a potency ratio in a specific cell-culture readout