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We applied the same statistical threshold, considering an sb-eQTL to be non-significant if the Storey q-value (FDR) was greater than 0.25
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All current evidence comes from preclinical animal and cellular studies, meaning its efficacy and safety in people remain unproven
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Customized steady-state constraints for parameter estimation in non-linear ordinary differential equation models
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doi: 10.1038/nrendo.2012.140 115 DruckerDJBuseJBTaylorKKendallDMTrautmannMZhuangDet al
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