In: StanleyCADe LeonDD, editors
Investigational GLP-1 patches use specialised technologies such as microneedles to deliver large peptide molecules across the skin barrier
A once-weekly injection that quiets food noise, reduces cravings, and supports steady weight loss from day one
While beneficial for patients with obesity and metabolic syndrome, unintended weight loss can be detrimental in Crohn's disease patients who already struggle with malnutrition, malabsorption, or disease-related cachexia
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Tat exposure has also been shown to directly influence the expression of adhesion molecules, such as VCAM-1 and ICAM-1, as well as inflammatory mediators like monocyte chemoattractant protein-1 (MCP-1) and -TNF- [193]