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Creatinine levels may decline alongside reductions in muscle mass, which can complicate kidney marker interpretation over time

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Acute pancreatitis has been reported with GLP-1 receptor agonists, though causality remains debated

The American Association of Clinical Endocrinology now recommends considering long-term pharmacotherapy for obesity management

207-OR: Myostatin inhibition synergizes with GLP-1R agonism to accelerate weight loss in male, obese nonhuman primates