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So when it comes to estrogen hormone replacement therapy, that is helping restore the insulin sensitizing effects of estrogen, we also know that estrogen HRT can improve lipid profiles and it can blunt the visceral fat accumulation that we typically see in menopause

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Insulin Some authors suggest that chronic hyperinsulinemia may act as a maladaptive mechanism, inducing SNS overactivity in obesity (Landsberg, 1986, 2001)