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instead of being a single GLP-1 receptor agonist like semaglutide, tirzepatide is a GLP-1/glucose insulinotropic peptide (GIP) dual agonist, which explains the greater weight loss it delivers
Clinical pharmacology biopharmaceutics review: Dulaglutide
It does not slot neatly into an endocrine signaling cascade
This biological hunger can hit all at once, leading to a restart of the binge cycle even when on medication , or can come back with a vengeance when finishing weight loss medication , if binge eating patterns have not been addressed separately
The clearance timeline also depends entirely on what you did before injection
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