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Pyroglutamate is a glutamate precursor whose CSF concentration is 120 M (58), rivaling the extracellular glutamine concentration of 400 M (basal glutamate is 2-3 M)
Martens, P
Sudden shifts in body composition can temporarily disrupt this hormonal equilibrium, leading to late periods, lighter flow, or skipped cycles
[26] [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur
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The direct consequence of TAZ mutation is the decrease in mature CL and the accumulation of monolysocardiolipin (MLCL), a precursor of CL, which has been shown to have a lower affinity for the respiratory chain complexes III and IV [3, 4]
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