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Rapid weight loss can shift phosphorus intracellularly, particularly during refeeding-like states, and hypophosphatemia below 2.0 mg/dL can cause generalized muscle weakness and cramping 11

10.1016/j.stem.2015.12.003 41 GeY.ZhengX.MaoS.ZhangQ.HuG.WeiY

Patients experiencing significant side effects may benefit from a slower titration schedule or temporary dose reduction, and dose escalation should be deferred while significant gastrointestinal symptoms persist

Meal delivery services work excellently for GLP-1 users

Are there alternative treatments available

This start-low,-go-slow approach balances efficacy with minimised GI side effects and improves adherence during the transition period