For musculoskeletal indications, most patients at our Doral clinic report a noticeable reduction in pain within 2 to 3 weeks and a functional improvement (range of motion, strength, load tolerance) by weeks 4 to 8
They rebuild damaged tissue
It should be noted that the musculoskeletal evidence base remains preclinical, a 2025 scoping review by McGuire and colleagues in Current Reviews in Musculoskeletal Medicine found no adequately powered randomised controlled trials
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Vitamin B12 shots are typically given intramuscularlymeaning the injection is delivered directly into a muscle, most often in the upper arm (deltoid), thigh, or buttock
The preclinical and animal studies indicate benefits for tendon and joint injuries, says Drew Timmermans, ND, a naturopathic physician and cofounder of Regenerative Performance in Arizona