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Common side effects include: Cognitive slowing, including difficulties with memory, concentration, and word-finding Fatigue and drowsiness Dizziness and coordination problems Paraesthesia (tingling sensations, particularly in the hands and feet) Decreased appetite and weight loss Mood changes, including low mood, depression, and irritability More serious risks include: Metabolic acidosis topiramate inhibits carbonic anhydrase, which can reduce blood bicarbonate levels
Oxidative stress does not produce a unique or reliable set of symptoms
Abushamat LA, Shah PA, Eckel RH, Harrison SA, Barb D
Its a health necessity
It is also known to mediate the migration of endothelial cells [97]
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