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When used in tandem with an established diet and exercise routine, Semaglutide offers substantial weight loss for obese or overweight patients who may also have high blood pressure, diabetes or high cholesterol

In contrast, the obesity-specific analysis focuses on adolescents who meet the CDC definition of obesity and have no prior evidence of T2D

Semaglutide works by mimicking the effects of GLP-1 (glucagon-like peptide-1), a naturally occurring hormone that plays a key role in regulating blood sugar and appetite

This was the first large-scale signal suggesting that GLP-1 therapy might modify the inflammatory response during pancreatitis

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doi: 10.1016/j.cmet.2013.06.018 62 PesslerFMayerCTJungSMBehrensEMDaiLMenetskiJPet al