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The biosynthesis of arachidonyl-CoA catalyzed by ACSL4 contributes to the execution of ferroptosis by triggering phospholipid peroxidation[116]
Duarte MB, Medeiros BZ, da Silva Lemos I, da Silva GL, Alano CG, Dondossola ER, Streck EL (2023) Melatonin improves behavioral parameters and oxidative stress in zebrafish submitted to a leucine-induced MSUD protocol
doi: 10.1534/genetics.117.201491 106 Navarro-GarciaF.SanchezM.NombelaC.PlaJ
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M.DanielianL
Future perspectives and concluding remarks Taken together, current evidence supports a revised view of ferroptosis as a tissue-level death program that can extend beyond the initiating cell
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