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Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering

Hara KY was supported by Grant-in-Aid for Young Scientists (B) (18769004, 22760608)

Cerebral small vessel disease and association with higher incidence of depressive symptoms in a general elderly population: the ages-reykjavik study
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Additional analytical methodologies may include mass spectrometrybased molecular mass confirmation, peptidemetal complex validation, and stability profiling under defined storage and handling conditions

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