When refrigeration is needed, travellers can: request a mini fridge from the hotel use a portable medication cooler keep medication in an insulated pouch with cooling packs Most hotels are familiar with requests for medication storage and are usually happy to assist
B12 also improves mental clarity and mood
It benefits from innovative technology based on liposomal encapsulation which protects it from gastric juices, thus increasing its absorption in the gut
There are anecdotes suggesting that creatine has other side effects
The most useful options fill gaps the medication creates: protein to protect muscle, fiber for constipation, fluids and electrolytes for hydration, and vitamin B12 plus other vitamins when blood work shows you are low
But it seems most common to see B12 half-life in plasma reported as 6 days, for example in the cyanocobalamin pharmaceutical insert : s3-us-west-2.amazonaws.com/