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Purine metabolites such as UA, inosine, and hypoxanthine are essential for maintaining redox balance and cellular energy homeostasis, with UA acting as a major endogenous antioxidant and other purines supporting ATP production

In contrast, for those on GLP-1RAs therapy for 6 months or less, the intercepts were negative for age and positive for gender, but again, the estimates for age and sex did not yield significant results, indicating a lack of influence from these variables on weight changes

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