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Change in BMI (%) Wegovy pen delivers significant, sustained BMI reduction at week 68 3,4 Supportive secondary end point 4 14.7% (~36 lb) mean weight reduction with Wegovy vs 2.7% (~6 lb) mean weight increase with placebo at 68 weeks Mean baseline body weight: Wegovy =242.3 lb

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To assess the safety of repeated oral MCT administration, body weight was monitored during the experimental period in stress-nave rats