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doi: 10.1097/HCO.0b013e3281532b53 79 SowersJR

Svolge un ruolo cruciale nella produzione di energia trasportando gli acidi grassi nei mitocondri delle cellule

IGF-1 was demonstrated to regulate MDM2 activity by inhibiting the association between p19ARF and MDM2 in a p38 MAPK-dependent manner (Heron-Milhavet and LeRoith, 2002)

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While effective for certain patients, daily dosing can be associated with systemic side effects, medication fatigue, and limited flexibility