glp 1 and kidney disease Renal effects of GLP-1 receptor agonists tirzepatide in individuals with type 2 diabetes: seeds of a promising future | Endocrine CKJ REVIEW GLP-1 receptor agonists

Nitrogen movement between hostand tumorin mice inoculatedwith EhrlichAscitic tumor cells

Journal of Neurology

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

However, both groups exhibited significantly reduced GSH levels compared with uninfected controls ( p 0.05)

10.1530/JOE-13-0414 19 WaiseT

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