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Key drivers behind GLP-1 and addiction research include: Rapid expansion in the use of GLP-1 medications such as semaglutide (Ozempic and Wegovy) and tirzepatide (Maunjaro and Zepbound) Reports of changes in cravings, alcohol use, or reward-seeking behaviors beyond weight loss Increased public conversation and clinical curiosity about psychological and behavioral effects Scientific interest in GLP-1 activity within reward pathways and dopamine signaling Recognition that appetite regulation and addiction involve shared neural mechanisms This research is still emerging, and findings should be interpreted with caution

GLP-1 receptor agonists also effectively reduce HbA1c while preserving beta-cell function, promote weight loss and do not cause hypoglycemia, DeFronzo said

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

Boutrid N et al