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Alzheimers disease is not simply a memory disease. It is a complex neurodegenerative process that often overlaps with insulin resistance, vascular disease, inflammation, mitochondrial stress, sleep disruption, and loss of metabolic resilience

Finally, 6-phosphogluconate dehydrogenase catalyzes an oxidative decarboxylation, proceeding through a keto intermediate and an enediol, to yield ribulose-5-phosphate and a second NADPH

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This is found in peroxisomes in most eukaryotic cells