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Up to now all the prospective GPR119 agonists were plagued by low bioavailability, lack of efficacy and more importantly, cardiotoxicity which has stopped all human studies before any large scale Phase III clinical trials (239)
More studies and case reports are necessary to ascertain long-term unknown harms and side-effects
These signs include inadequate blood sugar control, persistent side effects, or changes in weight
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Fed Pract 36:64 Gonzlez-Gonzlez O, Ramirez IO, Ramirez BI, Oconnell P, Ballesteros MP et al (2022) Drug stability: ich versus accelerated predictive stability studies
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