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Conclusion While supplements can certainly provide support for your bodys ability to better manage your cortisol response, they work best when youve created a solid base: quality sleep, a balanced and nutrient-dense diet, and regular exercise

25,3437 In patients who need to minimize weight gain or lose weight, addition of basal insulin is advised only after addition of other agents such as GLP-1 RAs, SGLT-2 inhibitors, or DPP-4 inhibitors

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Thus, surgical intervention may be necessary

Am J Epidemiol 152:11451153