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These findings emphasize the importance of GIPR activity and its anti-sclerotic role [32,33,34]
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Upon intravenous administration, ascorbic acid rapidly increases plasma concentrations, bypassing the limitations of gastrointestinal absorption that restrict oral dosing
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In individuals with type 2 diabetes, another phase 2 clinical study demonstrated that after 12 weeks of efinopegdutide treatment, although no significant improvement in glycated hemoglobin (HbA1c) levels was observed, the effect on weight loss reached a high of 7.9%, well above the 0.7% weight reduction rate in the placebo group
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