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Experiments have found that overexpression of the NF-B subunit and NF-B target genes in esophageal tissues of mice with GERD and down-regulation of the tight junction complexes, claudin1 and claudin4, resulted in esophageal barrier dysfunction in the mice
BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide fragment derived from a naturally occurring protein in the human gastric system
Longer peptides have more opportunities for synthesis errors, degradation, and aggregation
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doi:10.1371/journal.pone.0210389 [2] Wekwejt P, Wojda U, Kiryk A
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