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[PMID: 10401601] PubMed record related to this compound for laboratory literature review
The 'central planning' mechanism of GLP-1: from molecular signaling to systemic regulation GLP-1 is an incretin secreted by intestinal L cells, and its bioactive forms (GLP-1 (7-37) and GLP-1 (7-36) amide) have a half-life of only 2.1-2.4 minutes
Thus, oral chimeric GLP-1As that utilize ASBT-mediated endocytosis were developed, starting from an in silico design and progressing to in vitro / in vivo PKpharmacodynamic efficacies
On top of the benefits described above, these plans include additional benefits like dental, vision, fitness membership and even an allowance for healthy food
doi:10.3389/fnbeh.2019.00115
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