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Signs of a severe allergic reaction include trouble breathing, hives breaking out on the skin, swelling of the face and throat area, a fast heartbeat, or feeling like you might pass out

Bloating and sulfur burps round out the common GI complaints
Using both provides dual cardiovascular protection, limits individual risk factors, and helps determine whether this matters for your treatment strategy

In clinical studies of patients with pulmonary arterial hypertension (PAH), tadalafil-treated patients experienced improved exercise capacity and less clinical worsening compared to placebo

In the future, with the in-depth exploration of the mechanism of GLP-1R action and the development of multi-target agonists (e.g., GLP-1R/GIPR dual agonists), GLP-1R-related therapeutics are expected to make breakthroughs in a wider range of disease areas (e.g., nonalcoholic steatohepatitis, AD, etc.), providing a more precise and highly effective strategy for the treatment of metabolic diseases and related complications
