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In vitro studies, preclinical studies, retrospective studies and randomized clinical trials performed in Europe and the USA were included

The achievable regrowth ceiling is lower with advanced loss

The plot shows distinct clustering of cultures into their respective cohorts, indicating metabolic differences between each growth mode

[1] [4] The exact cause of the disease is unclear, but symptoms are a result of antibodies binding to receptors on the thyroid, causing over-expression of thyroid hormone

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