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Many of the effects of DPP-4 inhibitors in large-scale clinical trials, including their effects on atherosclerotic ischemic events, heart failure, sodium excretion, albuminuria and glomerular function may be meaningfully influenced by their actions to enhance of the endogenous stem-cell chemokine, SDF-1

There has been no head-to-head trial, so better depends on whether you weight early efficacy or established, obtainable evidence

These molecules can be recognized by pattern recognition receptors (PRRs) on the surface of immune cells, such as Toll-like receptors (TLRs)

[PMID: 1930278] PubMed record related to this compound for laboratory literature review

Liver metabolism

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