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The group also supported creating a shared clinical database that could help provide much needed clarity
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Fourth, long-term clinical outcomes data - cirrhosis incidence, HCC rates, liver transplantation, and liver-related mortality assessed as primary endpoints in randomized trials - are not yet available and are urgently needed to move beyond surrogate histological endpoints
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1 A meta-analysis of findings from 11 randomized controlled trials found SERM therapy with either clomiphene citrate or tamoxifen improved some sperm parameters and hormone levels, and more than doubled the pregnancy rate in couples affected by idiopathic male infertility
Pathol Oncol Res 2009
