The second part, which is utmost important, is limit
You may feel a slight sting from the injection, but this should subside quickly
In animal toxicology studies, no significant adverse effects have been observed even at doses far exceeding typical therapeutic ranges
For patient comfort, you may allow the semaglutide pen to reach room temperature before injection by removing it from refrigeration
PMID: 34626851 Dungan K, DeSantis A (2016): Glucagon-like peptide-1 receptor agonists for the treatment of type 2 diabetes mellitus
Ask for hormone level testing, including testosterone, estradiol, and DHEA-S