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If the patient can tolerate it, the dose is escalated to 1.7 mg (Wegovy) or 2 mg weekly (Ozempic) for the next four weeks and up to a maximum of 2.4 mg once weekly (Wegovy) afterwards as a maintenance dose
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Third-party labs may be used to test the potency of compounded medications and research compounds alike
10.1007/s00018-020-03688-4 185 O'NeillG
Compounded GLP-1s are a glucagon-like peptide-1 (GLP-1) receptor agonist which may be used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of: 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)
Some studies have shown that GLP-1 receptor agonists, including semaglutide, may have protective effects on the heart
