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As in F10 f/f LysM Cre mice, DIO studies in both male and female mice revealed no significant differences in HFD-induced weight gain (Figure 4G) or GTT (Figure 4H) between littermate F10 f/f mice and F10 f/f Villin Cre mice

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AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins