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All patients that satisfied these criteria were included, resulting in a final sample of 40 hypothyroidism (age mean 46 years, range 20 79 years, 4 males) and 12 CFS (mean age 43 years, range 23 68 years, 3 males) patients

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However, another report demonstrated mitochondrial stress and bioenergetics defects in GPx1 null mice ( Figure 3 ), and hence plays a key role in protecting phospholipids, cholesteryl esters and cardiolipin and defense against apoptosis and maintenance of ETC and OXPHOS ( + / - cells are sensitive to oxidative stress triggers (Muller et al., 2007)

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