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Six-month supplementation with high dose coenzyme Q10 improves liver steatosis, endothelial, vascular and myocardial function in patients with metabolic-dysfunction associated steatotic liver disease: A randomized double-blind, placebo-controlled trial

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10.1016/j.metabol.2009.10.007 46 DhillonS

Fiber supplementation must be introduced slowlyincreasing by 5 grams weeklyto minimize bloating and gas, which may be particularly problematic given semaglutide's effects on gastric emptying

According to FDA-approved prescribing information, gastrointestinal adverse effects occur commonly with these medications, with nausea reported in 16-44% of patients, vomiting in 6-24%, and abdominal pain or distension in 5-18%, depending on the specific medication and dosage

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