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Etiology The human gamma-glutamyl transpeptidase gene family is composed of at least seven different gene loci and several of them are located on the long arm of chromosome 22 [9]

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This raises the interesting possibility that Rab7 mediates contact site formation between LDs and lysosomes directly, or by promoting MCS formation between LDs and late endosomes/MVBs (amplisomes) and that late endosomes/MVBs at these MCS mature to form lysosomes (Schroeder et al., 2015)

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