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Given that doxorubicin-induced cardiac injury is driven by mitochondrial dysfunction, excessive ROS, impaired NO signaling, and NF-Bmediated inflammation, the convergence of AMPKNrf2 activation (metformin) with NF-B/NOX inhibition and NO restoration (allicin) provides a mechanistically consistent explanation for the enhanced cardioprotective profile observed with the combined therapy

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Some of the health benefits of levocarnitine include: Improved Performance: Can increase stamina and reduce fatigue during high-intensity workouts