Proton pump inhibitors effectively reduce symptoms by decreasing acid production, but symptoms typically return upon discontinuation
For example, gastrointestinal symptoms might disrupt sleep if they occur at night, or changes in eating patterns and weight loss could temporarily influence sleep architecture as the body adjusts
doi:10.1016/0006-291x(73)91459-9 Pickart L, Vasquez-Soltero JM, Margolina A
Rats treated with 0.5mg/kg/day intraperitoneal MOTs-C for 12 weeks were noted to have improved mechanical efficiency of the myocardium during exercise training over the placebo group.7 Data on the impact of exogenous MOTs-C on exercise tolerance in humans is not available, though, studies of endogenous MOTs-C levels have noted an 11.9 fold increase in MOTs-C levels in skeletal muscle in response to exercise, as well as increases in circulating levels of MOTs-C by 1.5 fold during exercise.5 MOTs-C is also of interest for a potential impact on longevity
Technique and target tissue affect outcomes
The 30-days-on, 30-days-off cycle we use at Perfect B is the standard protocol, both to optimize efficacy and maintain appropriate cycling practice