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Semaglutide also has warnings for pancreatitis, diabetic retinopathy complications, hypoglycemia that can be severe, acute kidney injury, acute gallbladder disease, hypersensitivity reactions, and pulmonary aspiration during general anesthesia or deep sedation

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The review also covered three therapeutic research strategies: direct GSH depletion (leading to ferroptosis or enhanced chemotherapy sensitivity), indirect approaches targeting the tumour microenvironment, and prodrug strategies utilising elevated tumour GSH for drug activation

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& Tschp, M