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IGF-1 is a growth and survival signal, so persistently high exposure raises a theoretical concern about feeding an existing malignancy

10.1186/s11658-024-00659-6 99 YangI

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Theres potential increased risk of sun-induced skin cancers due to melanin production changes, particularly with long-term skin lightening protocols

After cleansing, apply a vitamin C serum or a niacinamide-based product to further boost radiance

13 The bottom line Glutathione side effects are, for most people, mild and depend heavily on the form: oral means occasional digestive upset, injectable and IV mean injection-site reactions and a small risk of allergic reaction