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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition where the immune system destroys self, in this case the parietal cells of the stomach
& Poynard, T
DioLaz Canada
From a receptor pharmacology perspective, GLP-1 receptor agonists act through GLP-1R activation, a class B G-protein-coupled receptor signaling system with established systemic effects on appetite regulation, gastric emptying, glucose-dependent insulin secretion, metabolic control, and weight reduction (Drucker, 2025)
A small increase on the scale after starting creatine is usually water retention, not fat gain, or a sign that treatment stopped working
The variability likely relates to individual chromium status, with deficient individuals responding better than those with adequate levels
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