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Although -oxidation is impaired in the setting of VPA toxicity, this metabolite has a prolonged elimination half-life and could be responsible for the prolonged coma that is sometimes observed despite the normalization in plasma VPA concentrations [17, 18]

Persistent or severe symptoms warrant a prescriber discussion

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Conclusion Intermittent fasting isnt necessary to lose weight, but it is a popular and often effective strategy that works well for some people