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Methodology A retrospective, post-market observational study was conducted using data collected from VigiBase until June 2025, using mapped terms under Medical Dictionary for Regulatory Activities (MedDRA)
In the U.S., CVD is the leading cause of death, constitutes 17% of healthcare costs, and is estimated to increase in prevalence by ~10% and direct costs by almost three-fold over the next 20 years under current CVD prevention and treatment regimes [2]
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It also shows potential in eliminating the pro-inflammatory phenotype of senescent cells and improving the functional microenvironment of tissues
For people with type 2 diabetes who are also taking insulin or sulfonylureas, the risk is substantially higher and requires active monitoring and likely dose reductions of the diabetes medications as weight and blood glucose improve
GLP-1 drugs are an important part of how we manage obesity
