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Next, we evaluated the expression levels of SMA, which has been reported to be associated with cell contractility

I mean, you do a therapy to treat a condition and hopefully you can alleviate that condition and go to maintenance

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Recently, our group has demonstrated that PD mimetics including 6-hydroxydopamine (6-OHDA), N-methyl-4-phenylpridine (MPP + ) and rotenone suppressed mTOR signalling, accelerated cleavage of caspase-3 and PARP in PC12 cells and primary neurons and subsequently triggered neuronal apoptosis